Quality of life in patients with advanced gastric cancer: a randomized trial comparing docetaxel, cisplatin, 5-FU (TCF) with epirubicin, cisplatin, 5-FU (ECF)
نویسندگان
چکیده
منابع مشابه
Docetaxel-based chemotherapy in the treatment of gastric cancer.
Docetaxel-based chemotherapy appears to have considerable promise in advanced gastric cancer. In phase II studies of single agent docetaxel, response rates (RRs) of 17% to 24% have been achieved in previously untreated patients. Importantly, RRs of 20% to 22% are seen in second-line treatment. Work by a Swiss and Italian collaborative group has shown that the combination of docetaxel 85 mg/m(2)...
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BACKGROUND Unresectable biliary tract carcinoma (BTC) is associated with a very poor prognosis. To improve efficacy and tolerance of the 5-fluorouracil (5-FU)/cisplatin combination in BTC, we designed a new therapeutic schedule, the LV5FU2-P regimen. PATIENTS AND METHODS Twenty-nine patients with advanced or metastatic BTC were prospectively enrolled in the study. The treatment (LV5FU2-P regi...
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BACKGROUND Based on a phase I study showing the feasibility of combining of oxaliplatin, cisplatin, and 5-fluorouracil (5-FU) (OCF) with radiation therapy (RT) in esophageal cancer, the efficacy of this regimen in esophageal, gastroesophageal (GE), and gastric (G) cancer was assessed in this phase II multicenter study. PATIENTS AND METHODS Patients with resectable tumors were eligible. Treatm...
متن کاملcombination of 5-fu and epirubicin in the treatment of advanced gastric cancer
this study was undertaken to assess the effectiveness of 5-fu plus epirubicin in the treatment of the advanced gastric cancer. for this purpose, 22 patients with no previous treatment were studied. all of the patients were unoperable or metastatic. follow up checking continued for 24 months. our selected therapeutic regimen consisted of a combination of 500 mg/m2 5-fu dialy for five days, and 7...
متن کاملSalvage Treatment for Advanced Gastric Cancer Using FEP (5-FU, Etoposide, Cisplatin) Combination Chemotherapy.
PURPOSE There is no effective treatment for patients with advanced gastric cancer having failed to respond to first line chemotherapy. The aim of this study was to evaluate the therapeutic activity, and safety, of a FEP regimen in patients with a recurrence of, or metastatic, gastric cancer that had been unresponsive to primary chemotherapy. MATERIALS AND METHODS Recurred or metastatic gastri...
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ژورنال
عنوان ژورنال: BMC Cancer
سال: 2006
ISSN: 1471-2407
DOI: 10.1186/1471-2407-6-274